Durlstotherium is an extinct genus of mammal from the Early Cretaceous. It contains a single species, Durlstotherium newmani. The type specimen was found in Durlston Bay, Dorset, after which the genus was named. D. newmani was named after a British pub landlord, Charlie Newman. Durlstotherium and two of its contemporaries, Tribactonodon and Durlstodon, had tribosphenidan (three-cusped) molars, which are an advanced characteristic among eutherian mammals and suggest that the group emerged earlier than the Early Cretaceous.
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